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目的探讨呼吸机在抢救高压氧治疗禁忌的急危重症CO中毒患者中的价值。方法选取1990年11月~2000年11月份收住我院的急危重症CO中毒患者45例作为对照组,给予常规导管/面罩吸氧氧疗。选取2002年11月~2011年11月份收住我院的急危重症CO中毒患者43例作为观察组,给予气管插管,建立人工气道,予以呼吸机治疗(BILEVEL模式)。两组患者均给予了防治脑水肿、促进脑细胞功能恢复、防治并发症、维持内环境稳定等综合治疗。结果观察组平均神志恢复时间短于对照组;并发症少于对照组;平均住院时间短于对照组;迟发性脑病少于对照组;死亡率低于对照组。结论存在高压氧治疗禁忌证的CO中毒的急危重症患者,在早期使用呼吸机治疗可明显减轻病情,缩短住院时间,改善预后。
Objective To investigate the value of ventilator in the treatment of critically ill patients with CO poisoning treated with hyperbaric oxygen. Methods Forty-five acute critically ill patients with CO poisoning who were hospitalized in our hospital from November 1990 to November 2000 were selected as the control group, and received conventional catheter / mask oxygen therapy. Forty-three patients with acute and severe CO poisoning admitted to our hospital from November 2002 to November 2011 were selected as the observation group. Endotracheal intubation was given and the artificial airway was established. The patients were treated with ventilator (BILEVEL mode). Two groups of patients were given prevention and treatment of brain edema, promote brain cell function recovery, prevention and treatment of complications, to maintain the stability of the internal environment and other comprehensive treatment. Results The average recovery time of conscious group in observation group was shorter than that in control group. The complication was less than that of control group. The average length of hospital stay was shorter than that of control group. Delayed encephalopathy was less than that of control group. The mortality rate was lower than that of control group. Conclusions In patients with critically ill CO poisoning with hyperbaric oxygen therapy contraindications, early use of ventilator therapy can significantly reduce the disease, shorten the hospital stay and improve the prognosis.