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目的观察盐酸氨溴索治疗慢性阻塞性肺疾病(COPD)急性加重期的临床疗效及用药安全。方法将2009年6~12月北京市石景山医院呼吸科收治的66例COPD患者随机分成治疗组和对照组,治疗组应用盐酸氨溴索(每次30mg,tid,po),对照组应用必嗽平,观察两组治疗方法的患者在咳嗽、咯痰方面的疗效。结果治疗组总有效率91.6%,对照组总有效率73.3%。治疗组总体疗效优于对照组(P<0.05)。结论盐酸氨溴索对COPD急性加重期具有良好的治疗效果。
Objective To observe the clinical efficacy and safety of ambroxol hydrochloride in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods Sixty-six patients with COPD admitted to Department of Respiratory Medicine, Shijingshan Hospital, Beijing from December to December in 2009 were randomly divided into treatment group and control group. Ambroxol hydrochloride (30mg, tid, po) was used in the treatment group, Flat, observe the two groups of treatment methods in patients with cough, expectoration efficacy. Results The total effective rate was 91.6% in the treatment group and 73.3% in the control group. The curative effect of the treatment group was better than that of the control group (P <0.05). Conclusion Ambroxol hydrochloride has a good therapeutic effect on acute exacerbation of COPD.