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目的了解廊坊市健康人群脊髓灰质炎(脊灰)抗体水平。方法采取分层多级抽样的方法,调查廊坊市10个县(市、区)的<1岁、1～2岁、3～4岁、5～6岁、7～9岁、10～14岁、15～19岁、≥20岁健康人群共1 632人,并收集被调查人血液样本,检测其血清中脊灰中和抗体水平。结果脊灰Ⅰ、Ⅱ、Ⅲ型中和抗体的阳性率分别是97.7%、97.3%、97.5%,抗体几何平均滴度(Geometric Mean Titers,GMT)分别为1∶73.76、1∶78.55、1∶74.44。抗体GMT随年龄增长逐渐下降。不同性别、户籍、地区和免疫史间抗体水平差异无统计学意义。结论廊坊地区健康人群脊灰抗体水平良好,免疫屏障牢固。
Objective To understand the level of poliomyelitis (polio) antibodies in healthy population in Langfang City. Methods A stratified multistage sampling method was adopted to investigate the prevalence and risk factors of hypertension in Langfang city in 10 counties (cities and districts) of <1 year old, 1 ~ 2 years old, 3 ~ 4 years old, 5 ~ 6 years old, 7 ~ 9 years old, 10 ~ 14 years old , A total of 1 632 healthy people aged 15 ~ 19 years old and ≥20 years old, and the blood samples of the respondents were collected to detect the level of poliovirus neutralizing antibody in their serum. Results The positive rates of neutralizing antibodies of type Ⅰ, type Ⅱ and type Ⅲ were 97.7%, 97.3% and 97.5%, respectively. The Geometric Mean Titers (GMT) were 1:73.76, 1:78.55 and 1: 74.44. Antibody GMT gradually decreased with age. There was no significant difference in antibody levels between different gender, household registration, regional and immunization history. Conclusion The level of poliovirus in healthy population in Langfang area is good and the immune barrier is firm.