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目的探讨慢性再生障碍性贫血(CAA)患者红细胞输注的临床疗效。方法回顾分析1995年1月-2007年8月住院的425名CAA患者无效输血的发生情况及其与年龄、性别、输血前血红蛋白(Hb)浓度、输血次数及既往输血量的关系。结果425名CAA患者中,出现无效输注者39名(912%);输注的1 416U红细胞制剂中,249U(17.6%)为无效输注。无效输注与患者年龄、性别和输血前Hb浓度无关,与输血次数和既往输血量有关。结论CAA患者的无效输血与其输血次数及既往输血量有关。输血次数越多,既往输血总量越大,则无效输注的发生率越高。
Objective To investigate the clinical efficacy of erythrocyte infusion in patients with chronic aplastic anemia (CAA). Methods The incidence of ineffective blood transfusion in 425 CAA patients hospitalized from January 1995 to August 2007 was retrospectively analyzed, and its relationship with age, sex, hemoglobin (Hb) concentration before transfusion, number of blood transfusion and blood transfusion volume were retrospectively analyzed. RESULTS: Of the 425 patients with CAA, 39 (912%) had failed transfusions; 249U (17.6%) of the 1 416U transfused infusions were ineffective. Invalid infusion and age, gender and transfusion of Hb concentration has nothing to do with the number of transfusions and previous transfusion related. Conclusions Invalid blood transfusion in CAA patients is related to the number of blood transfusions and blood transfusion volume. The more the number of blood transfusions, the greater the total amount of previous transfusions, the higher the incidence of invalid infusions.