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Objective:To observe the therapeutic effects of plum-blossom needle tapping combined with the modified Yangxue Dingfeng Tang (a decoction for nourishing the blood and expelling wind) for the localized neurodermatitis. Methods: 141 cases of the localized neurodermatitis were randomly divided into 3 groups. Forty-seven patients in the treatment group received local tapping and oral medication of the modified Yangxue Dingfeng Tang which consisted of Sheng Di Huang (生地黄 Radix Rehmanniae),Dang Gui (当归 Radix Angelicae Sinensis), Chi Shao (赤芍 Radix Paeoniae Rubra), Tian Dong (天冬 Radix Asparagi), Mai Dong (麦冬 Radix Ophiopogonis), Jiang Can (僵蚕 Bombyx Batryticatus), Mu Dan Pi (牡丹皮 Cortex Moutan), Chuan Xiong (川芎 Rhizoma Chuanxiong), He Shou Wu (何首乌Radix Polygoni Multiflori), and Quan Xie (全蝎 Scorpio). Forty-seven patients in the control group Ⅰwere simply given the modified Yangxue Dingfeng Tang; and 47 patients in the control group Ⅱ were treated with oral benadryl and Vitamin C plus local extal application of 10% urea ointment. The treatment course for all the 3 groups lasted 30 days. Results: The short-term and long-term effects for the treatment group were much better than those of the 2 control groups (P<0.05). Conclusion: The plum-blossom needle tapping plus the modified Yangxue Dingfeng Tang exhibits a better and stable effect for the localized neurodermatitis.