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该文通过六组大鼠实验,用光镜和电镜方法,观察治疗矽肺新药——合68的治疗效果,用正常鼠做空白对照,矽肺鼠做实验对照,用克矽平,汉甲素,克矽平+合68做相互对照,实验用一次气管注入染尘,待矽结节基本形成,开始药物治疗,染尘后100天解剖,制做光镜和电镜标本,肺干重结果用t检验法统计。结果发现,合68组肺干重高于正常组(t>0.01),低于矽肺组(t>0.01),与各治疗组间无差别,肺脏矽结节纤维化为Ⅱ—Ⅲ级,比矽肺组低,与各治疗组接近。扫描镜下,合68组肺组织结构紊乱,肺泡
This article through six groups of rat experiments, using light microscopy and electron microscopy methods to observe the treatment of silybium new drug - Heyi 68 treatment effect, with normal rats as blank control, pneumoconiosis mice as experimental control, with chlorpheniramine, anthraquinone, Kefuping + Hexi 68 was used as a cross reference. The experiment used a trachea to inject the dust, and the formation of pupal nodules was basically completed. The drug treatment was started. The dust was dissected after 100 days and the light and electron microscope specimens were made. The results of lung dry weight were used. Test statistics. The results showed that the dry weight of lungs in group 68 was higher than that of normal group (t>0.01) and lower than that of silicosis group (t>0.01). There was no difference between the treatment groups and the pulmonary fibrosis of nodules was grade II-III. The silicosis group was low and close to the treatment groups. Scanning microscope, combined with 68 groups of lung structural disorder, alveolar