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目前产科和新生几监护日益完善,但脑瘫仍是未解决的问题。因而了解其已知病因所占发病比率,调查未知病因,从而找出预防和治疗方法甚为重要。本文研究美国12所医学院1959~1966年54,000次分娩,出生的婴儿均随访至7岁。结果:孕前母亲智力障碍是诱发子代发生脑瘫的重要因素。其它孕前因素为:分娩过运动缺陷的子代,产母有甲亢、癫痫史或两次以上死胎史。此类因素引起的脑瘫占发病例数的4.4%以上。妊娠期诱因为:妊娠中期,24小时尿蛋白排出量超过5g(有时伴高血压),妊娠晚期出血等。分娩发动后最重要的诱因是胎龄在32周以下。
At present, the guardianship of obstetric and newborn babies is improving day by day. However, cerebral palsy remains an unresolved issue. Therefore, it is very important to find out the prevention and treatment methods to find out the incidence rate of the known etiology and to investigate the unknown etiology. This article studies 54,000 deliveries from 1959 to 1966 in 12 U.S. medical schools. All infants born at birth are followed up to 7 years of age. Results: Premarital mothers’ mental retardation was an important factor in inducing cerebral palsy in children. Other pre-pregnancy factors are: offspring of childbirth motor deficiencies, birth mother with hyperthyroidism, history of epilepsy or two or more stillbirths. Cerebral palsy caused by such factors accounted for more than 4.4% of the number of cases. Pregnancy incentives are: mid-pregnancy, 24-hour urine protein excretion more than 5g (sometimes with hypertension), bleeding in the third trimester. The most important cause of labor after birth is gestational age below 32 weeks.