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目的了解清远市无偿献血人群HBsAg阳性分布情况。方法 2010-2014年清远市无偿献血者121 114人份,采用ELISA法进行双试剂检测,分别按年度、性别、年龄、文化程度、地区对检测结果进行回顾性分析。结果清远市2010-2014年无偿献血者HBsAg总阳性率为1.39%。男性与女性无偿献血者HBsAg总阳性率差异有统计学意义(χ~2=96.89,P<0.05),男性高于女性。不同年龄段无偿献血者HBsAg总阳性率差异无统计学意义(P>0.05),18~岁年龄段HBsAg阳性率呈逐年下降趋势。不同文化程度的无偿献血者HBsAg总阳性率差异有统计学意义(χ~2=545.01,P<0.05),初中以下学历的无偿献血者HBsAg阳性率较高。不同地区的无偿献血者HBsAg总阳性率差异有统计学意义(χ~2=193.78,P<0.05),三连地区和阳山县阳性率较高。结论 5年来清远市无偿献血人群HBsAg阳性率相对稳定,北部山区阳性率较高,存在一定的人口学特征差异,应严格进行献血者筛选,提高检测水平,以确保血液安全。
Objective To understand the positive distribution of HBsAg in unpaid blood donors in Qingyuan City. Methods A total of 121 114 unpaid blood donors from 2010 to 2014 in Qingyuan City were enrolled in this study. ELISA was used to detect double agents. Retrospective analysis was made on the detection results by year, sex, age, educational level and region. Results The total positive rate of HBsAg in unpaid blood donors from Qingyuan in 2010-2014 was 1.39%. The positive rate of HBsAg in male and female unpaid blood donors was statistically significant (χ ~ 2 = 96.89, P <0.05), and higher in males than in females. There was no significant difference in the total positive rate of HBsAg among different age groups (P> 0.05). The positive rate of HBsAg in 18 ~ age group showed a declining trend year by year. The positive rate of HBsAg in unpaid blood donors with different educational level was statistically significant (χ ~ 2 = 545.01, P <0.05). The positive rate of HBsAg in unpaid blood donors with junior high school education was higher. The positive rates of HBsAg in unpaid blood donors in different areas were statistically significant (χ ~ 2 = 193.78, P <0.05), and the positive rates were higher in Sanlian and Yangshan counties. Conclusions The positive rate of HBsAg in unpaid blood donors in Qingyuan City in the past five years is relatively stable. The northern mountainous region has a high positive rate, and there are some demographic differences. Blood donors should be screened strictly to improve the detection level to ensure blood safety.