自从杂交瘤技术建立以来,McAb的制备技术得到很大的发展,McAb的需要量也日以增多,但由于制备单抗腹水所用的BALB/c小鼠,饲养条件要求较高,腹水产量较低等问题,致使McAb的价格昂贵,给临床应用带来困难。为此,本实验采用NIH鼠代替BALB/c鼠制备单克隆抗体腹水,并与BALB/c小鼠进行 Since the establishment of hybridoma technology, McAb technology has been greatly developed, the demand for McAb also increased day by day, but due to the preparation of monoclonal antibody ascites BALB / c mice, breeding conditions require higher ascites production is lower And other issues, resulting in the expensive McAb, to clinical difficulties. To this end, in this experiment, NIH mice instead of BALB / c mice monoclonal antibody ascites prepared and BALB / c mice