目的:观察早产儿早期洗肠对高胆红素血症的影响。方法:将早产儿132例,随机分为对照组和实验组,将实验组患儿于生后6 h内开始给予洗肠,1次/d,持续至胎粪排完为止。结果:实验组患儿血清胆红素水平、光疗发生率明显低于对照组,黄疸消退时间也明显短于对照组。结论:早产儿早期洗肠有利于血清胆红素下降,降低血清胆红素峰值,缩短黄疸消退时间,避免胆红素脑病的发生。 Objective: To observe the effect of early diarrhea on hyperbilirubinemia in premature infants. Methods: 132 cases of preterm infants were randomly divided into control group and experimental group. The experimental group started to wash the intestines within 6 hours after birth, once per day until the end of meconium was exhausted. Results: Serum bilirubin levels and the incidence of phototherapy in the experimental group were significantly lower than those in the control group, and the regression time of jaundice was also significantly shorter than that in the control group. Conclusion: Early bowel washing is beneficial to the decrease of serum bilirubin, the decrease of serum bilirubin, the shortening of jaundice subsidence time and the avoidance of bilirubin encephalopathy.