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伴发于病毒感染、系统性红斑狼疮、干燥综合征或血清病的皮肤血管炎可表现为荨麻疹样皮疹,但荨麻疹性血管炎(UV)常有免疫复合物介导性疾病的证据而不伴结缔组织病或感染,个别损害可持续24小时以上,消退后留紫癜性色泽。患者常伴有胃肠道症状,关节痛,葡萄膜炎,肾损害,发热,雷诺氏现象,神经受累,慢性阻塞性肺部疾病,肌炎和血管性水肿。治疗上,系统投用皮质类固醇激素常有效,抗组胺药、消炎痛、抗疟药、免疫抑制剂仅在一些病人中有效。作者试用秋水仙碱治疗二例对其它药物无效的患者。
Skin vasculitis associated with viral infections, systemic lupus erythematosus, Sjögren’s syndrome or serum sickness can manifest as a urticaria-like rash, but urticaria vasculitis (UV) is often evidence of immune complex-mediated disease Not associated with connective tissue disease or infection, the individual damage sustainable 24 hours or more, after leaving the purpura color. Patients are often accompanied by gastrointestinal symptoms, joint pain, uveitis, kidney damage, fever, Raynaud’s phenomenon, neurological involvement, chronic obstructive pulmonary disease, myositis and angioedema. Treatment, the system administration of corticosteroids are often effective, antihistamines, indomethacin, antimalarial drugs, immunosuppressive agents effective only in some patients. The authors tried colchicine to treat two patients who were ineffective with other drugs.