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目的:探讨血清甲状旁腺激素M(PTHM)含量测定对诊断慢性肾功能衰竭(CRF)导致的继发性甲状旁腺功能亢进(SHP)的临床价值和意义。方法:利用双抗放射免疫测定法对271例CRF患者作血PTHM含量测定。结果:约86%的患者血PTHM含量>27ng/dl的正常参考水平,其中约25%的患者血PTHM含量>200ng/dl。血PTHM含量和患者的年龄或性别不存在相关性,但血PTHM含量和患者经历血液透析年限呈正相关(r=0600)。结论:血PTHM测定对诊断SHP有重要的临床价值,并对SHP的监测有一定的参考价值。
Objective: To investigate the clinical value and significance of serum parathyroid hormone M (PTHM) in the diagnosis of secondary hyperparathyroidism (SHP) caused by chronic renal failure (CRF). Methods: 271 CRF patients were tested for PTHM by double-antibody radioimmunoassay. RESULTS: Approximately 86% of patients had normal reference levels of PTH-M> 27 ng / dl, with approximately 25% of patients having PTH-M levels> 200 ng / dl. Blood PTH M content and age or gender of the patient does not exist, but the blood PTH M content and patient experience hemodialysis was positively correlated (r = 0 600). Conclusion: PTH M determination of blood on the diagnosis of SHP has important clinical value, and monitoring of SHP have some reference value.