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为了确定强力霉素对于控制霍乱弧菌传染的效力,在加尔各答对住院的霍乱病人的家属接触者使用了强力霉素治疗。 1978年4～8月间,将59例霍乱标志病例(细菌学上建立)的276个家属接触者分为两组。口服单剂量强力霉素组137人,15岁以上的成年人口服300毫克;15岁以下者按每公斤体重给予6毫克。体重与年龄比例特殊的,则根据印度医学会的报告计算。为避免药物可能对胃肠道的刺激,服药前可先吃些饼干。3个月以下的婴儿不列入研究范
To determine the efficacy of doxycycline in controlling Vibrio cholerae infection, doxycycline was used in contact with relatives of chronically infected patients in Kolkata. Between April and August 1978, 276 family contacts of 59 cases of cholera markers (bacteriologically established) were divided into two groups. 137 oral single-dose doxycycline group, adults over the age of 15 oral 300 mg; 15 years of age were given 6 mg per kg body weight. Weight and age ratio of special, according to the Indian Medical Association report calculations. In order to avoid possible gastrointestinal stimulation of drugs, medication may be to eat some biscuits. Infants under 3 months are not included in the study