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本文报道对50例慢性腹泻患儿作小肠粘膜活检、粘膜乳糖酶活性分析和粪便还原糖测定。结果:粪糖阳性率70%,乳糖酶缺乏68%,其中两者皆存者28例(占56%)。78%患儿有不同程度的肠粘膜损害,其损害的程度可能决定乳糖不耐受的发生率。表明继发乳糖不耐受是腹泻的一常见并发症,可能是腹泻持续的一个重要因素。乳糖酶活性测定为一较可靠的诊断方法,可用以指导临床饮食治疗。
In this paper, 50 cases of children with chronic diarrhea intestinal mucosal biopsy, mucosal lactase activity analysis and determination of reducing sugars. Results: The positive rate of fecalose was 70%, lactase deficiency was 68%, of which 28 were both (56%). 78% of children have different degrees of intestinal mucosal damage, the degree of damage may determine the incidence of lactose intolerance. Show that secondary lactose intolerance is a common complication of diarrhea and may be an important factor in the continuation of diarrhea. Determination of lactase activity as a more reliable diagnostic method can be used to guide the clinical diet.