论文部分内容阅读
无症状HBsAg携带者合并δ肝炎病毒(HDV)感染可导致严重肝损害。由于目前的免疫学检测方法尚不能从血液中检出滴度极低的δ抗原,HDV感染的直接证据仅能从肝组织活检获得,因此测定血清抗-δ更有实用意义。为了确定抗-δ在无症状HBsAg携带者中的临床意义,作者对2,487例无症状HBsAg携带者(男1,413例,女1,074例,年龄14～61岁,平均35岁)采用放射免疫法测定血清抗-δ,并对肝功能异常者做肝活检。
Asymptomatic HBsAg carriers in combination with hepatitis delta virus (HDV) infection can cause severe liver damage. Because of the current immunological detection methods can not be detected from the blood of very low titer δ antigen, direct evidence of HDV infection can only be obtained from liver biopsy, so the determination of serum anti-δ more practical significance. To determine the clinical significance of anti-delta in asymptomatic HBsAg carriers, the authors measured the serum levels of 2,487 asymptomatic HBsAg carriers (1,413 males and 1,074 females, aged 14-61 years, mean 35 years) by radioimmunoassay Anti-delta, and liver biopsy of those with abnormal liver function.