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1 造血嵌合性产生的对供体特异的免疫耐受性人类在大约半个世纪以前第一次发现造血嵌合性可以产生供体特异的免疫耐受性。Billingham等发明一种用小白鼠进行皮肤移植实验方法,在研究中发现,基因型相同的个体之间进行皮肤移植,皮肤成活好;而基因型不同的个体之间
1 Hematopoietic chimerism produces donor-specific immune tolerance Humans first discovered hematopoietic chimerism about half a century ago to produce donor-specific immune tolerance. Billingham et al. Invented a mouse skin transplantation experimental method, in the study found that individuals with the same genotype were skin grafts, the skin survived; and genotypes between different individuals