目的　分析山西地区 2 4例严重急性呼吸道综合征 (SARS)死亡病例临床特征及导致死亡危险因素。方法　对 2 0 0 3年 3月 7日至 6月 4日山西地区 2 4例 SARS死亡病例的临床资料进行回顾性分析。结果　 2 4例患者男 13例 (5 5 % ) ,女 11例 (4 6 % ) ;主要临床表现为发热、咳嗽、畏寒、气促等。发病早期的白细胞总数 ,淋巴细胞总数下降。胸部 X线显示肺部斑片状阴影 ,短期内病灶增多 ;7d内死亡 3例 (12 % ) ,7～ 14 d死亡 11例(4 7% ) ,14 d以上死亡 10例 (4 4 % ) ;14例 (5 0 % )病人有基础疾病 ,其中 4例 (16 % )糖尿病 ,4例 (16 % )脑血管病 ,3例 (12 % )心血管病 ,6例 (2 5 % )高血压 ,其中 7例 (2 9% )同时合并 2种以上疾病 ;2 4例中直接死于 SARS19例(79% ) ,死于基础疾病 5例 (2 1% ) ;多因素分析结果显示 :年龄 >5 0岁、有无心理治疗、早期淋巴细胞计数为影响死亡危险因素。结论　年龄 >5 0岁、早期淋巴细胞计数降低是该病死亡危险因素 ;心理治疗是保护因素 Objective To analyze the clinical characteristics and risk factors of death in 24 severe acute respiratory syndrome (SARS) patients in Shanxi Province. Methods The clinical data of 24 deaths from SARS in Shanxi Province from March 7 to June 4, 2003 were retrospectively analyzed. Results There were 13 cases (54%) and 11 females (46%) in 24 cases. The main clinical manifestations were fever, cough, chills, shortness of breath and so on. The incidence of early white blood cells, the total number of lymphocytes decreased. Thoracic X-ray showed patchy shadows in the lungs, and the number of lesions was increased in a short period of time. Three patients died within 7 days (12%), 11 (47%) died within 7 to 14 days and 10 patients (14%) died within 14 days ; 14 patients (50%) had underlying diseases, of which 4 (16%) had diabetes mellitus, 4 (16%) had cerebrovascular disease, 3 (12%) had cardiovascular disease and 6 Of the 24 cases, 19 (79%) died of SARS directly and 5 (21%) died of underlying disease. Multivariate analysis showed that the age > 50 years old, with or without psychotherapy, early lymphocyte count as a risk factor for death. Conclusion Age> 50 years old, early lymphocyte count is a risk factor for death; Psychotherapy is a protective factor