糖类皮质激素于1948年 Hench 氏首先以 ACTH 治疗类风湿关节炎获得显著效果以来,激素用于临床已整整卅二年了。临床实践证明它在某些疾病的诊断和治疗中确有明显之效果。应用广泛。但也有很多副作用,现仅就临床应用中的有关问题作一简要的介绍,以供临床工作中参考。一、肾上腺皮质的生理解剖知识(一)生理解剖:肾上腺位于肾脏之上极,是成对器官,相当于第十一胸椎(左)和十二胸椎(右)的水平,右呈三角形,左呈半月形,其重量约11—18克,平均15克,男大于女。肾上腺分皮质和髓质二部份,皮质来自中胚层,髓质来自外胚层。皮质占重量 Glucocorticoids Since Hench’s first successful treatment of rheumatoid arthritis with ACTH in 1948 has been clinically used for exactly two years. Clinical practice has proved that it has certain effects in the diagnosis and treatment of certain diseases. Wide range of applications. However, there are many side effects, and only a brief introduction on the related issues in clinical application is provided for reference in clinical work. First, the physiological anatomy of the adrenal cortex (A) physiological anatomy: the adrenal gland in the pole on the pole, is a pair of organs, equivalent to the eleventh thoracic (left) and twelve thoracic (right) level, the right triangle, the left Was half-moon shaped, weighing about 11-18 grams, an average of 15 grams, more than men and women. Adrenal cortex and medulla two parts, cortex from mesoderm, medulla from ectoderm. Cortex accounted for weight