目前临床应用的喹诺酮类抗菌药对厌氧菌无抗菌活性或仅对其中的少数有很低的抗菌活性,而新近合成的一些喹诺酮类抗菌药(包括左氧氟沙星、司氟沙星、格帕沙星、trovafloxacin、克林沙星及DU-6859a等)所具有的一个重要特征为提高了对厌氧菌的抗菌活性,治疗厌氧菌所致的感染有良好的疗效.本文对上述新喹诺酮类抗菌药对厌氧菌的抗菌活性及临床应用作一简要介绍. At present, quinolone antibacterials have no antibacterial activity against anaerobic bacteria or only a few of them have low antibacterial activity. Some newly synthesized quinolone antibacterials (including levofloxacin, levofloxacin, , Trovafloxacin, clinifloxacin and DU-6859a, etc.) have an important feature to improve the antibacterial activity of anaerobic bacteria, the treatment of infections caused by anaerobic bacteria have a good effect.In this paper, the new quinolone antibacterial drug pairs Antibacterial activity of anaerobic bacteria and clinical application for a brief introduction.