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为确定皮质类固醇治疗对HELLP综合征的效果,尤其是不同剂量治疗对孕妇实验室值及孕龄的影响,对1995年3月~1999年7月间37例产前诊断为HELLP综合征(血小板<100 000/mm~3,天冬氨酸转移酶≥70 U/L,乳酸脱氢酶>600 U/L)的孕妇进行回顾性分析。将研究对象分3组,1组11例,未经皮质类固醇治疗;2组15例,为促胎肺成熟采用标准剂量皮质类固醇治疗,每12小时肌肉注射12 mg倍他米松共2次或每6小时静脉注射6 mg地塞米松共4次;3组
In order to determine the effect of corticosteroid therapy on HELLP syndrome, especially the effect of different doses on laboratory values and gestational age of pregnant women, 37 prenatal diagnoses of HELLP syndrome (platelet) from March 1995 to July 1999 <100 000 / mm ~ 3, aspartate aminotransferase ≥ 70 U / L, lactate dehydrogenase> 600 U / L) were retrospectively analyzed. Subjects were divided into three groups, one group of 11 cases, no corticosteroid treatment; two groups of 15 cases, to promote fetal lung maturity standard dose corticosteroid therapy, intramuscular injection of 12 mg betamethasone a total of 12 times every 12 hours or 6 hours intravenous injection of 6 mg dexamethasone 4 times; 3 groups