随着中药安全性评价的广泛开展,毒性病理学在中药毒性研究中的重要性也日益凸显。临床常用的山豆根作为一种有毒中药,若使用不当,会使机体产生严重的毒性反应甚至导致死亡。综述近年来山豆根的毒性病理学研究进展,主要包括山豆根所致的神经毒性、肝毒性、胃肠毒性等。 With the extensive evaluation of the safety of traditional Chinese medicines, the importance of toxicological pathology in the study of toxicity of traditional Chinese medicines has also become increasingly prominent. As a poisonous traditional Chinese medicine, the commonly used medicinal root of Radix solanaceae, if used improperly, will cause serious toxic reaction and even cause death. In recent years, the research progress of toxicity pathology of the root of Radix solanacearum mainly includes neurotoxicity, hepatotoxicity and gastrointestinal toxicity caused by Radix solanacearum.