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目的:探析降钙素原在诊断早期新生儿感染中的意义。方法:以化州市人民医院收治的87例早期感染新生儿,根据新生儿感染的程度分为轻度感染组(n=43)和重度感染组(n=44),另选取同时间段到本院检查的42例身体健康的新生儿为对照组,所有新生儿均接受降钙素原水平检测。结果:经检测,重度感染组、轻度感染组患儿的降钙素原水平均高于对照组(P<0.05);重度感染组患儿的降钙素原阳性率、分级情况均高于其他两组(P<0.05)。结论:在诊断早期新生儿感染中,降钙素原水平的诊断准确率相对较高,可对早期新生儿感染进行客观的评价,为临床合理用药提供正确指导,提升新生儿的生存质量。
Objective: To investigate the significance of procalcitonin in the diagnosis of early neonatal infection. Methods: A total of 87 early neonates who were admitted to Huazhou Municipal People’s Hospital were divided into mild infection group (n = 43) and severe infection group (n = 44) according to the degree of neonatal infection. Forty-two healthy newborns examined in our hospital were control subjects, and all newborns received procalcitonin levels. Results: The levels of procalcitonin in severe infection group and mild infection group were higher than those in control group (P <0.05). The positive rate and grade of procalcitonin in severe infection group were higher than those in other groups Two groups (P <0.05). Conclusion: The diagnostic accuracy of procalcitonin is relatively high in the diagnosis of early neonatal infection, which can objectively evaluate the early neonatal infection and provide correct guidance for clinical rational drug use and improve the quality of life of neonates.