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美国铀登记处对1944年一次爆炸性事故中暴露于可溶性天然铀化合物的3名患者,于38年后对铀的吸入量和沉积量进行了重新估价。根据事故后短期内获得的间断性尿铀排泄资料,估算出初始肺沉积量为40～50mg铀。据个人排泄曲线估算了初始长期骨沉积量,暴露水平最高的患者为410μg(5.2Bq),对骨表面产生的40年累积剂量当量为～2msv(200mrem)。事故后38年对其中2例进行了医学和保健物理学方面的检查,结果没有发现可测得的铀,也未发现由于暴露于铀而引起的任何体征。在暴露者中,有1例于事故后短期内显示出清除模型的改变,可能与伴随吸入酸性烟雾引起的肺水肿有关。
The Uranium Registry of United States conducted a revaluation of uranium intake and sedimentation 38 years after three years of exposure to soluble natural uranium compounds in an explosive accident in 1944. According to intermittent uranium excretion data obtained shortly after the accident, it is estimated that the initial lung deposition is 40-50 mg uranium. The initial long-term bone deposition was estimated from an excretion profile of 410 μg (5.2 Bq) for patients with the highest exposure and ~ 2 msv (200 mrem) for a 40-year cumulative dose on the bone surface. Thirty-eight years after the accident, medical and physico-chemical examinations were performed on two of these cases. As a result, no measurable uranium was found and no signs of uranium exposure were found. Among the exposed individuals, one showed short-term changes in the clearance model after the accident, possibly related to pulmonary edema associated with inhalation of acid smoke.