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目的:对妥洛特罗贴剂应用于咳嗽变异性哮喘儿童的效果进行对比分析。方法:随机挑选南方医科大学附属东莞市人民医院2013年2月-2014年2月收治的咳嗽变异性哮喘儿童患者70例,将他们随机分为观察组和对照组两组,每组各35例。对照组患儿采用常规哮喘治疗方法,在此基础上,观察组患儿采用妥洛特罗贴剂进行治疗,比较两组患儿的临床疗效,对治疗前后的超敏C反应蛋白、血Ig E值以及外周血EOS计数进行比较,并观察两组患者的不良反应发生情况。结果:观察组的治疗效果明显优于对照组患者,且超敏C反应蛋白、血Ig E值以及外周血EOS计数减少幅度要比对照组大,差异有统计学意义(P<0.05)。结论:妥洛特罗贴剂对于治疗儿童咳嗽变异性哮喘具有良好的效果,可以极大地减少患儿的不良反应,治疗时间短,见效快。
OBJECTIVE: To compare and analyze the effect of tulobuterol patch on children with cough variant asthma. Methods: Seventy patients with cough variant asthma were randomly selected from Dongguan Children’s Hospital of Southern Medical University from February 2013 to February 2014. They were randomly divided into observation group and control group, with 35 cases in each group . The control group of children with conventional asthma treatment methods, on this basis, the observation group of children treated with tulobuterol patch, the clinical efficacy of two groups were compared before and after treatment of high-sensitivity C-reactive protein, blood Ig E value and peripheral blood EOS count were compared, and two groups of patients with adverse reactions were observed. Results: The therapeutic effect of the observation group was significantly better than that of the control group. The reduction of the high-sensitivity C-reactive protein, IgE and peripheral blood EOS in the observation group was larger than that in the control group (P <0.05). Conclusion: The use of tulobuterol patch for the treatment of children with cough variant asthma has a good effect, can greatly reduce the adverse reactions in children, the treatment time is short, quick.