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许多尿路结石是含钙的和许多病人有高尿钙症,在他们的结石形成中可作为一个共同特性。Pak和其他学者的研究,曾经提示许多病人不管他们钙的摄入量多少而24小时尿钙排出225mg。偶然在未证实有代谢缺陷的大个儿男性病人可达300mg。但是在一般情况下,24小时尿钙超过225mg的病人必须认为可能与不正常排钙有关,应作为检查的指征,以阐明其高尿钙症的潜在机制。本组先前的研究已经显示:包含各种不同质的饮食,对正常个体的每日排钙量并无任何程度的影响,对照空腹尿钙、血清钙、肾小球滤过率可将病人概括分成三类:肠道过度吸收的高尿钙症、原发性甲旁亢症甲状旁腺素的影响下溶骨性高尿钙症,较小一部分似乎是肾内钙处理的缺陷(这些已特称为肾性高尿钙症或所谓的肾性漏钙)。
Many urolithiasis are calcium-containing and many patients have hypercalciuria and can serve as a common feature in their formation of stones. Studies by Pak and others have prompted many patients to excrete 225 mg of 24-hour urinary calcium regardless of their calcium intake. Occasionally did not confirm a metabolic defect in large men up to 300mg of patients. However, in general, patients with a 24-hour urinary calcium excretion of more than 225 mg must be considered to be associated with abnormal calcium discharge and should be used as an indication of the test to clarify the underlying mechanism of hypercalciuria. This group of previous studies have shown that: contains a variety of different quality of diet, the daily discharge of normal individuals did not have any effect on the amount of calcium control, fasting urine calcium, serum calcium, glomerular filtration rate can be summarized Divided into three categories: hypercalciuria with overexpression of the gut, hyperparathyroidism under the influence of parathyroid hormone in primary hyperparathyroidism, the smaller part seems to be deficient in intrarenal calcium treatment (these have been Special called renal hypercalciuria or so-called renal calcium leak).