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目的探讨脑少突胶质肿瘤常见MRI表现与组织病理学分级的关系。方法通过观察104例少突胶质肿瘤的发生部位、形态、边缘、境界、信号特点、囊变、出血、浸润范围、水肿程度、占位效应、强化方式及强化程度等MRI表现,分析不同观察指标与病理学分级的差异,明确肿瘤MRI表现与WHO分级之间的关系。结果额叶62例,颞叶24例,顶叶13例,枕叶、小脑、侧脑室、鞍区、桥小脑角区、扣带回、四脑室、丘脑各有少数病例发生。肿瘤发生部位、形态、边缘、境界、信号、水肿、囊变及强化程度8项观察指标在不同WHO分级的少突胶质肿瘤之间无统计学差异(P>0.05)。肿瘤浸润范围、出血、占位效应、不同强化形式4项观察指标在不同WHO分级的肿瘤之间有统计学差异(P<0.05)。结论肿瘤出血、浸润范围、占位效应和强化形式等常见MRI表现与少突胶质肿瘤的组织病理学分级有关,可作为判断少突胶质肿瘤良恶性程度的参考指标。
Objective To investigate the relationship between MRI findings and histopathological grade in brain oligodendrocytes. Methods The MRI findings of 104 oligodendrogliomas were analyzed in terms of their location, morphology, margins, realms, signal characteristics, cystic changes, hemorrhage, infiltration range, degree of edema, mass effect, enhancement mode and degree of enhancement The difference between the index and pathological grade, and the relationship between tumor MRI manifestations and WHO classification. Results There were 62 cases of frontal lobe, 24 cases of temporal lobe, 13 cases of parietal lobe, occipital lobe, cerebellum, lateral ventricle, saddle region, cerebellopontine angle area, cingulate gyri, fourth ventricle and thalamus. Tumor location, morphology, margins, realms, signals, edema, cystic degeneration and degree of enhancement of the eight indicators in different WHO grade oligodendroglioma between no significant difference (P> 0.05). There were significant differences in tumor infiltration range, hemorrhage, space-occupying effect and different intensified forms in 4 WHO-graded tumors (P <0.05). Conclusions The common MRI findings such as tumor hemorrhage, infiltration range, mass effect and enhanced form are related to the histopathological grade of oligodendrocytes, which can be used as a reference index to judge the degree of malignancy of oligodendrocytes.