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[目的]了解福建省伤寒、副伤寒(伤寒)发病规律,掌握流行趋势,为制订伤寒的防治对策提供科学依据。[方法]对2004～2010年福建省伤寒疫情资料进行分析。[结果]2004～2010年福建省累计报告伤寒3 341例,年均发病率为1.33/10万。伤寒发病率(/10万),2004～2010年分别为1.80、1.42、1.51、1.08、1.23、1.18、1.13(P<0.01)。2004～2010年年均发病率(/10万),最高的是宁德市(2.88)、龙岩市(2.80)、厦门市(2.77);男性为1.44,女性为1.22(P<0.01);0～4岁为2.86,5～14岁为1.25,15～34岁为1.31,35～54岁为1.17,55～74岁为1.13,≥75岁为1.19。2004～2010年的3 341例伤寒病人中,5～10月发病的占61.33%;农民占22.96%,学生占15.41%,散居儿童占10.98%。2006年厦门市城区内发生伤寒流行,1月1日至7月31日报告病例190例,分离菌株中主要为甲型副伤寒沙门菌,流行原因为养殖地贝类被污染。其他病例均为散发。2006～2010年累计从伤寒病人分离出伤寒病原菌102株,其中伤寒沙门菌占30.39%,甲型副伤寒沙门菌占53.92%,乙型副伤寒沙门菌占13.73%,丙型副伤寒沙门菌占1.96%。[结论]2004～2010年福建省伤寒发病率维持在较低水平,5岁以下儿童和青壮年为发病的重点人群。
[Objective] To understand the rule of typhoid fever, paratyphoid fever and typhoid fever in Fujian Province, master the epidemic trend and provide a scientific basis for the prevention and control of typhoid fever. [Method] The data of typhoid fever in Fujian from 2004 to 2010 were analyzed. [Results] A total of 3 341 cases of typhoid fever were reported in Fujian Province from 2004 to 2010, with an average annual incidence of 1.33 / 100 000. Typhoid fever incidence (/ 100,000), 2004 ~ 2010 were 1.80,1.42,1.51,1.08,1.23,1.18,1.13 (P <0.01). The average annual incidence rate was 100000 in 2004-2010, the highest was Ningde (2.88), Longyan (2.80), Xiamen (2.77), the male was 1.44 and the female was 1.22 (P <0.01) 4 years old was 2.86,5 to 14 years old was 1.25, 15 to 34 years old was 1.31, 35 to 54 years old was 1.17, 55 to 74 years old was 1.13, ≥75 years old was 1.19. Between 2004 and 2010, 3 341 cases of typhoid fever From May to October accounted for 61.33%; farmers accounted for 22.96%, students accounted for 15.41%, scattered children accounted for 10.98%. In 2006, typhoid epidemics occurred in the urban areas of Xiamen City. From January 1 to July 31, 190 cases were reported, and Salmonella paratyphi A was the main isolates in the isolates. The epidemic reason was that the shellfish in the breeding areas were contaminated. Other cases are distributed. From 2006 to 2010, a total of 102 strains of typhoid pathogenic bacteria were isolated from typhoid fever patients, among which Salmonella typhi accounted for 30.39%, Salmonella paratyphi A accounted for 53.92%, Salmonella paratyphi A 13.73%, Salmonella paratyphi C 1.96%. [Conclusion] The incidence of typhoid fever in Fujian Province was kept at a low level from 2004 to 2010. The children under 5 years of age and the young and middle-aged adults were the key patients.