自上世纪七十年代以来,食管下段腺癌的发病率在西方国家上升了350%以上,此癌惟一公认的癌前病变是Bar rett食管(BE)。这是极常见的胃食管反流性疾病(GERD)的并发症之一。由于食管腺癌预后差,5年生存率低,因此对BE的诊断和治疗是预防食管腺癌的主要途径。目前,对BE的诊断依赖于内镜和病理学诊断。本文对此两种诊断标准作一简要综述。 Since the 1970s, the incidence of adenocarcinoma in the lower esophagus has risen by more than 350% in Western countries, and the only recognized precancerous lesion of this cancer is the Bar rett esophagus (BE). This is one of the most common complications of gastroesophageal reflux disease (GERD). Because of the poor prognosis of esophageal adenocarcinoma, 5-year survival rate is low, so the diagnosis and treatment of BE is the main way to prevent esophageal adenocarcinoma. Currently, the diagnosis of BE relies on endoscopic and pathological diagnosis. This article gives a brief overview of these two diagnostic criteria.