论文部分内容阅读
选择体重300～400克的雄性豚鼠10只,随机分成两组,每组5只。实验组用硫酸铍(BeSO_4·4H_2O上海化学试剂采购供应站)作为致敏原,每次用量为500微克(相当于铍25.5微克),注入豚鼠四爪皮下及背颈皮内,即每个部位每次注射100微克(相当5.1微克铍),每周致敏一次,连续4次,间隔一周后再以同样剂量加强免疫一次。对照组注射同等容量的生理盐水。一周后测定免疫指标,并作局部病理组织学检查。实验结果:淋巴细胞转化率两次测定结果都是
Ten male guinea pigs weighing 300-400 g were selected and randomly divided into two groups of five. Experimental group with beryllium sulfate (BeSO 4 · 4H 2 O Shanghai Chemical Reagent procurement supply station) as the allergen, each dosage of 500 micrograms (equivalent to 25.5 micrograms of beryllium) into guinea pigs under the skin and dorsal four feet, that is, each site Each injection of 100 micrograms (equivalent to 5.1 micrograms of beryllium), sensitized once a week for 4 consecutive times, one week after the interval and then boosted with the same dose once. The control group was injected with the same volume of saline. A week after the determination of immune indicators, and for local histopathology. Experimental results: Lymphocyte conversion rate of two measurements are