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目前 ,关于边缘区Ｂ淋巴细胞的对照定位机制不甚明确。研究显示 (Ｓｃｉｅｎｃｅ 2 0 0 2 ,2 97:4 0 9- 412 ) ,边缘区表达整合素淋巴细胞功能性抗原 (ｌｙｍｐｈｏｃｙｔｅｆｕｎｃｔｉｏｎ ａｓｓｏｃｉａｔｅｄａｎｔｉｇｅｎ 1,ＬＦＡ 1)、α4β1以及它们与配体ＩＣＡＭ 1
At present, the control mechanism of borderline B lymphocytes is not clear. Studies have shown (Science 2 0 0 2, 2 97: 4 0 9- 412) that the marginal zone expresses lymphocyte function associated antigen 1 (LFA 1), α 4β 1 and their interaction with the ligand ICAM 1