在子宫内感染风疹的儿童后来发生多发性先天性损害,包括白内障、视网膜色素沉着、耳聋、心脏导常和小头畸形。本病是非进行性的。作者研究了3例引起与先天性风疹相同损害的病人、早期病程与本病的其他病人不能鉴别。 3例确定或推测为先天性风疹的病人有一进行性神经系统损害,开始于10～20岁,特征性表现为痉挛状态、共济失调,智能衰退及抽搐发作。两例血清及 Children with rubella in the uterus subsequently developed multiple congenital lesions, including cataract, retinal pigmentation, deafness, cardiac abnormalities, and microcephaly. The disease is non-progressive. The authors studied 3 patients who caused the same lesions as congenital rubella, with no early identification of other patients with this disease. Three patients with confirmed or suspected congenital rubella had a progressive neurological impairment, beginning at 10 to 20 years of age, and were characterized by spasticity, ataxia, intellectual decline and seizures. Two cases of serum and