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目的 探讨胃肠道恶性肿瘤术后肿瘤复发性肠梗阻的临床特点以及病因诊断的要点。方法 以手术探查结果作为标准,回顾性地对91 例胃肠道恶性肿瘤术后肠梗阻病人在病理、病程、临床症状和体征、癌胚抗原(CEA)检测等方面进行统计分析。结果 肿瘤复发组病人原发肿瘤的分化程度较非复发组低下,肿瘤分期也较晚(P<0-05) ,复发组肠梗阻病程明显长于非复发组( P<0-01) ;两组在肠梗阻主要症状、腹部包块、不完全性肠梗阻和结、直肠梗阻的发生率上均存在显著差异( P< 0-01) ;复发组CEA阳性率和平均值(13-06 ±10-36)μg/L,均明显高于非复发组( P< 0-05) 。结论 两组间的上述差异点可作为胃肠道恶性肿瘤术后肿瘤复发性肠梗阻病因诊断的要点因素。
Objective To investigate the clinical features of recurrent intestinal obstruction after gastrointestinal cancer surgery and the main points of etiological diagnosis. Methods The results of surgical exploration were used as the criteria to retrospectively analyze 91 patients with intestinal obstruction after gastrointestinal malignancy in terms of pathology, disease course, clinical symptoms and signs, and CEA detection. Results The primary tumors in the tumor recurrence group had a lower degree of differentiation than the non-relapsed group, and the tumor staging was also late (P<0-05). The duration of intestinal obstruction in the recurrent group was significantly longer than that in the non-recurrent group (P<0-01); There were significant differences in the incidence of main symptoms of intestinal obstruction, abdominal masses, incomplete intestinal obstruction, and obstruction of the rectum (P < 0-01); the positive rate and mean value of CEA in the recurrent group (13-06 ± 10) -36)μg/L, significantly higher than non-recurrent group (P< 0-05). Conclusion The above differences between the two groups can be used as the main factors of the etiological diagnosis of recurrent ileus after gastrointestinal cancer.