胎粪吸入综合征是因在宫内或产时胎儿吸入混有胎粪的羊水,生后出现以呼吸窘迫为主要临床表现的综合征。下呼吸道的机械性阻塞和化学性炎症是其主要病理改变。严重的胎粪吸入综合征常表现为顽固性的低氧血症、心力衰竭,甚至休克,病死率甚高。该病多见于足月或过期产儿。活产儿中 Meconium aspiration syndrome is due to intrauterine or intrapartum fetal inhalation of fetal meconium amniotic fluid mixed with respiratory distress as the main clinical manifestations of syndrome. Mechanical obstruction of the lower respiratory tract and chemical inflammation are the major pathological changes. Serious meconium aspiration syndrome often presents with intractable hypoxemia, heart failure, and even shock, with a high case fatality rate. The disease more common in term or expired children. Live children