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1992年8月至1998年5月,我科对慢性阻塞性肺疾病患者伴急性呼吸衰竭采取了药物和机械通气治疗,取得了较好治疗效果,现分析如下。 1 资料和方法 1.1 一般资料 63例患者中,男38例,女26例,年龄53～72岁,平均住院时间21天,病程8～25年,平均病史13年,符合1977年第二次全国肺心病专业会议制订的诊断标准。出现肺性脑病40例(64％),严重意识障碍17例(27％)。经吸氧、控制呼吸道感染、解痉平喘、肾上腺皮质激素抗炎、纠正水、电解质平衡紊乱及营养支持等综合药物治疗,病情进行性加重,PaCO_2持续上升,pH逐渐下降,pH≤7.25,采用硅胶管经鼻插管进行机械通气治疗。
August 1992 to May 1998, our department of chronic obstructive pulmonary disease patients with acute respiratory failure took the drug and mechanical ventilation, and achieved good results, are analyzed as follows. 1 Materials and Methods 1.1 General Information 63 patients, 38 males and 26 females, aged 53 to 72 years, the average length of stay of 21 days, duration of 8 to 25 years, an average of 13 years of history, in line with the second national in 1977 Pulmonary heart disease professional conference to develop diagnostic criteria. Pulmonary encephalopathy occurred in 40 cases (64%), severe disturbance of consciousness in 17 cases (27%). Through the oxygen inhalation, respiratory tract infection control, antispasmodic and antiasthmatic, anti-inflammatory adrenal cortical hormone, water and electrolyte balance disorders and nutritional support and other comprehensive drug treatment, progressive aggravating conditions, PaCO_2 continued to rise, pH gradually decreased, pH ≤ 7.25, using silica gel Transnasal intubation for mechanical ventilation treatment.