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目的:分析非甾体类抗炎药物相关溃疡的临床特征。方法:回顾性分析非甾体类抗炎药物相关溃疡患者64例(观察组)的临床资料,并与同期未服用非甾体类抗炎药物消化性溃疡患者(对照组)临床资料进行比较。结果:观察组年龄构成、心、脑血管病史、消化道症状、溃疡发生部位与对照组比较,差异均有统计学意义(P<0.01或P<0.05)。结论:非甾体类抗炎药物相关溃疡>60岁老人多见,临床症状多不典型,常以出血、穿孔等并发症为首要症状;且胃溃疡发生率高于十二指肠溃疡,胃溃疡多位于胃窦部大弯侧。
Objective: To analyze the clinical characteristics of nonsteroidal anti-inflammatory drug-related ulcers. Methods: The clinical data of 64 patients (observation group) with nonsteroidal anti-inflammatory drug-related ulcer were retrospectively analyzed and compared with the clinical data of patients without peptic ulcer (non-steroidal anti-inflammatory drugs) Results: There were significant differences in age constitution, heart and cerebrovascular disease history, gastrointestinal symptoms and ulcer site between the observation group and the control group (P <0.01 or P <0.05). CONCLUSIONS: Non-steroidal anti-inflammatory drug-related ulcers are common in more than 60-year-olds and have mostly atypical clinical symptoms. Bleeding and perforation are the most common symptoms. The incidence of gastric ulcer is higher than that of duodenal ulcer and stomach Ulcers are located in the greater curvature of the antrum side.