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目的验证A-I型前列腺穿刺器对临床上前列腺特异性抗原(PSA)>4ng/ml和(或)前列腺直肠指诊、B超发现结节者进行前列腺癌筛查的临床意义。方法采用A-I型前列腺穿刺器,对36例PSA>4ng/ml或有前列腺结节者,在食指引导下进行前列腺左右叶的尖、中间、尾部和触及结节处活检。结果有结节者17例中发现前列腺癌(PCA)5例(29.4%);PSA>4.0ng/ml的34例中,PCA检出15例(44.12%)。分析显示:A-I型前列腺穿刺器与B-超引导系统相比较,对血清PSA>4.0ng/ml者的PCA检出率有明显的差异(x2=5.568, P<0.05)。结论A-I型前列腺穿刺器完全可以满足临床对筛查前列腺癌的要求,是一种操作简便、易用、费用低廉的前列腺疾病的诊断器械,值得临床推广。
Objective To verify the clinical significance of A-I prostatic puncture for prostate cancer screening in patients with clinically prostate specific antigen (PSA)> 4ng / ml and / or prostate and digital rectal examination. Methods A-I prostate puncture was performed on 36 patients with PSA> 4ng / ml or with prostatic nodules under the guidance of the index finger, and the biopsy was performed on the tip, middle and tail of the left and right prostatic leaves. Of the 17 patients with nodules, 5 (29.4%) had prostate cancer (PCA) and 15 (44.12%) had PCA with PSA> 4.0 ng / ml. Analysis showed that the detection rate of PCA in patients with serum PSA> 4.0ng / ml was significantly different (χ2 = 5.568, P <0.05) compared with B-superconducting system. Conclusion A-I type of prostatic puncture can meet the clinical requirements of screening for prostate cancer, is a simple, easy-to-use, inexpensive diagnostic tool for prostate disease, worthy of clinical promotion.