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对５０例先天性甲状腺功能减低症（简称甲低）病儿进行治疗及随访观察，其中男２１例，女２９例，开始治疗年龄３个月～１２岁，平均４．６７岁。结果表明，甲低病儿经甲状腺片替代治疗２周左右症状均减轻；对４５例进行５年随访观察，３７例平均３２．５个月身高达正常水平，２４例平均５３．９个月骨龄达正常水平，智能发育正常和显著进步３１例，另１４例略有进步。３个月以下开始治疗智能均达正常水平。体格和智能发育与治疗前的血清甲状腺素水平无关。甲状腺未发育者预后差。通过疗效分析提示，早期诊断、早期治疗对甲低病儿的疗效和预后有重要的影响。
Fifty patients with congenital hypothyroidism (Hypothyroidism) were treated and followed up, including 21 males and 29 females. The treatment ranged from 3 months to 12 years (average 4.67 years). The results showed that the symptoms of hypothyroidism after thyroid replacement therapy were relieved in about 2 weeks; 45 cases were followed up for 5 years, 37 cases averaged 32.5 months, up to normal level, 24 cases averaged 53.9 months bone age Up to normal levels, normal intelligence and significant progress in 31 cases, the other 14 cases a slight improvement. 3 months following the treatment of intelligence reached the normal level. Physical and mental development was not related to pretreatment serum thyroxine levels. Poor prognosis of undeveloped thyroid. Through the analysis of curative effects, early diagnosis and early treatment have a significant impact on the therapeutic effect and prognosis of children with hypothyroidism.