伯氨喹啉合并乙胺嘧啶作为预防及抗疟常用药。我科于1977年6月先后收治因服预防剂量伯喹及乙胺嘧啶2—5天而引起溶血性贫血及黄疸5例。主要临床表现明显贫血貌,酱油色尿,呕吐,厌食,精神萎靡,重者卧床不起,面色苍白,嗜睡或烦躁,反应低钝,巩膜轻度黄染。实验室检查黄疸指数最高1例为50单位,最低为9单位,凡登白间接强阳性,而麝香草酚浊度试验及谷丙转氨酶均正常,尿隐血 Primary quinoline combined pyrimethamine as a preventive and antimalarial commonly used drugs. Our department in June 1977 has been admitted to prevent propofol doses of primaquine and pyrimethamine 2-5 days caused hemolytic anemia and jaundice in 5 cases. The main clinical manifestations of anemia, soy sauce, urine, vomiting, anorexia, apathetic, severe bedridden, pale, drowsiness or irritability, low response blunt, scleral mild yellow dye. Laboratory examination of jaundice index 1 case of up to 50 units, a minimum of 9 units, where Dengden indirect strong positive, and thymol turbidity test and alanine aminotransferase were normal, urine occult blood