普通变异免疫缺损症的特点是低免疫球蛋白血症和感染率增高。它的发病机制十分复杂,有的以 B 细胞原发功能缺损为主,有的以 T 细胞功能障碍为主要机制,有的 B 细胞与 T 细胞功能都有障碍。即使 B 细胞,其功能障碍的特点亦因病人而异。我们报导了4例普通变异免疫缺损症患者的 B 和T 淋巴细胞的不同功能缺损状态。本文报 Common features of mutated immune deficiency are characterized by low immunoglobulin and increased infection rates. Its pathogenesis is very complicated, some of the primary defects in the primary B cells, and some T cell dysfunction as the main mechanism, and some B cells and T cell dysfunction. Even with B cells, the characteristics of their dysfunctions vary from patient to patient. We report the different functional deficits of B and T lymphocytes in 4 patients with normal mutated immunity. This article reported