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经导管肝动脉途经灌注化疗药物、栓塞的介入法是治疗中晚期肝癌最有效的非手术疗法之一。但治疗时出现各种并发症应引起人们的重视。笔者1997—1998年对50例患者在采用介入法治疗肝癌过程中,对患者出现的各种并发症进行分析和处理,现报道如下。1 临床资料1.1 一般资料 本组50例患者,年龄29～75岁,平均52岁。男42例,女8例。原发性肝癌41例,转移性肝癌9例。均经过B超、CT或MRI确诊。1.2 方法 用Seldinger法。经股动脉插管,将导管插入肝动脉或超选至肿瘤供血血管,经过1～4次治疗,灌注EPI、DDP、MMC、5-Fu等化疗药物,同时注入碘油乳剂或明胶海棉等栓塞物以堵塞病变血管减少肿瘤血供。
Transcatheter arterial infusion of chemotherapeutic drugs and embolization are one of the most effective non-surgical therapies for the treatment of advanced hepatocellular carcinoma. However, the occurrence of various complications during treatment should arouse people’s attention. In 1997-1998, the author analyzed and dealt with various complications of 50 cases of patients undergoing interventional therapy for liver cancer. 1 Clinical data 1.1 General information The group of 50 patients, aged 29 to 75 years old, average 52 years old. 42 males and 8 females. There were 41 cases of primary liver cancer and 9 cases of metastatic liver cancer. All were diagnosed by ultrasound, CT or MRI. 1.2 Methods Seldinger method. Through the femoral artery catheterization, the catheter is inserted into the hepatic artery or superselected to the tumor blood supply blood vessels. After 1-4 treatments, EPI, DDP, MMC, 5-Fu and other chemotherapy drugs are injected, and lipiodol emulsion or gelatin sponge is injected at the same time. Embolism to block the diseased blood vessels reduces tumor blood supply.