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目的体腔热灌注治疗恶性胸水腹水的疗效观察及毒副反应观察。方法共40例恶性肿瘤患者。其中12例为胸腔积液，28例为腹腔积液，均确诊为恶性胸腔积液、恶性腹腔积液。应用体腔热灌注仪器，给予体腔热灌注，应用顺铂或卡铂治疗。一般治疗3-4次，每隔4-5天一次。结果 C R：10例， P R：28例，S D：2例。结论应用体腔热灌注仪治疗恶性胸水、腹水的疗效高，局部无明显副反应，心肺功能无衰竭患者均能耐受。应用体腔热灌注仪治疗恶性胸水、腹水是可行的。“,” Objective The treatment effect observation and toxin side effect observation Which are hyperthermia perfusion treatment Malignant have some methods. Methods There are 40 cases of patients with malignant tumors which are 12 cases of Pleural Effusion and 28 cases of Abdominal Effusion.They are al diagnosed as Malignant Pleural Effusion、Malignant Abdominal Effusion. With the apply of hyperthermia perfusion’ apparatus, perfusion medicine is rendered to the treatment of hyperthermia perfusion with CISPLATIN FOR INJECTION or CARBOPLATIN FOR INJECTION, treating 3-4per4-5days. Results The outcomes are 10 cases of CR, 24 cases of PR, 6 cases of SD. Conclusions we draw a conclusion. The treatment that the apply of hyperthermia perfusion’s apparatuses to Malignant Pleural Effusion and Malignant Abdominal Effusion is high efficacy. The patients who have no obvious side effect in the part and whose lungs and have no prostration al can use them. The apply of hyperthermia perfusion’s apparatus treating Malignant Pleural Effusion and Malignant Abdominal Effusion is feasible.