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清洗和成形根管将在根管壁形成一涂层(smear layer,玷污层)。不少学者认为,涂层能抑制封闭剂与牙体的紧密结合和治疗药物的扩散,从而影响根管治疗效果。许多溶液都可用于此涂层的去除,但疗效不一。近年来的研究证实,四环素类药物具有抑制哺乳动物胶原酶活性作用,被用于牙周治疗。本研究目的是评价盐酸强力霉素(DH)去除涂层的效果。 48只人上颌磨牙腭侧根,分为2大组,采用Weine介绍的传统台阶根管制备技术,清洗和制备时第一组
Cleaning and shaping the root canal will create a smear layer on the root canal wall. Many scholars believe that the coating can inhibit the sealing agent and the close combination of teeth and the proliferation of therapeutic drugs, thus affecting the effect of root canal therapy. Many solutions are available for this coating, but with different effects. In recent years, studies have confirmed that tetracycline drugs inhibit the activity of mammalian collagenase, was used for periodontal treatment. The purpose of this study was to evaluate the effect of doxycycline hydrochloride (DH) on coating removal. Forty-eight human maxillary molars with palatal root were divided into 2 groups, using the traditional step root canal preparation technology introduced by Weine, the first group of cleaning and preparation