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本文采用胞二磷胆碱、ATP、CO-A、甘露醇、尼莫地平、维E烟酸脂胶囊、维生素C和鲁米那等综合疗法治疗大面积脑梗塞病人24例,与使用低分子右旋糖酐、维脑路通、甘露醇或(和)地塞米松治疗27例病人进行了疗效比较,治疗观察时间为2周,综合治疗组疗效明显高于对照组(P<0.05)。在治疗组内进行了治疗前后两周静脉血中检测水溶性脂质过氧化物(WSFS)及脂溶性过氧化物(LPO)的自身对照研究,治疗前后无明显变化。治疗组内4例死亡病人,其中3例作了脑剖检。
In this paper, citicoline, ATP, CO-A, mannitol, nimodipine, vitamin E nicotinate capsules, vitamin C and luminal and other comprehensive treatment of 24 patients with large area cerebral infarction, and the use of low molecular weight Dextran, Venoruton, mannitol or (and) dexamethasone treatment of 27 patients were compared for the treatment of observation time of 2 weeks, the comprehensive treatment group was significantly higher than the control group (P <0.05). Self-control study of WSFS and LPO in venous blood before and after treatment in the treatment group had no significant change before and after treatment. Four patients died in the treatment group, of which three were brain biopsy.