近年来由于抗癌药物的广泛应用,药物性间质性肺炎有增多的趋势,其病理改变是不可逆的,呈进行性加重,应引起高度重视。药物引起肺部形态学的改变有:1.实质性损害,如肺泡嗜伊红细胞浸润,巨噬细胞浸润或以变态反应为主的肉芽肿等。临床症状呈多种表现。停止用药或给予激素治疗多可恢复。2.因肺泡损伤所引起的病变,如巨噬细胞浸润型的一部分和肺泡增殖、化生的肺实质及肺间质的改变以及组织蛋白的胶原化等,此型 In recent years due to the widespread use of anti-cancer drugs, drug-induced interstitial pneumonia have an increasing trend, the pathological changes are irreversible, progressive increase, should be highly valued. Drugs cause lung morphological changes are: 1. Substantial damage, such as alveolar eosinophil infiltration, macrophage infiltration or allergic granuloma and so on. Clinical symptoms showed a variety of performance. Stop medication or give hormone therapy and more recoverable. 2. due to alveolar damage caused by lesions, such as a part of macrophage infiltration and alveolar proliferation, metaplasia of the lung and the interstitial lung interstitial changes and collagen protein, etc., this type