结肠黑变病的色素形成是由于上皮内和上皮下的巨噬细胞吞噬了因泻药引起的凋亡的粘膜上皮细胞。尽管开展了许多组化研究,但色素的组成成分仍未明确。此种复杂的色素有自体荧光性,并表现出脂褐质(与年龄相关)的组化特性。虽然植物血凝素组化法已被用于检出脂褐质和各种蜡样质色素的糖成分,但它未被用于结肠黑变病色素的研究,研究欲弥补此空白。 方法:8例结肠黑变病患者和3例健康者 Colitis melanosis is caused by macrophages in the epithelial and subepithelial phagocytosis of laxative-induced apoptosis of mucosal epithelial cells. Although many studies have been conducted on the composition of the pigment, the composition of the pigment remains unclear. Such complex pigments are autofluorescent and exhibit lipofuscin (age-related) histochemical properties. Although phytohemagglutinin has been used to detect the sugar content of lipofuscin and various waxy pigment, it has not been used to study the pigment of colorectal melanosis, and research is to make up for this gap. Methods: 8 patients with melanosis and 3 healthy subjects