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目的:探讨细菌感染性肺炎患儿血清白细胞介素-6(IL-6)、降钙素原(PCT)及超敏C反应蛋白(hs-CRP)水平与肺功能的相关性。方法:抽取2018年5月至2019年9月孟州市人民医院收治的210例住院患儿，根据住院期间是否发生细菌感染性肺炎分为阳性组(110例)和阴性组(100例)，检测两组患儿血清IL-6、PCT和hs-CRP水平，并对血清IL-6、PCT及hs-CRP水平与肺功能进行相关性分析。结果:相对于阴性组，阳性组IL-6、PCT和hs-CRP水平均高于对照组(n P<0.05)；肺功能Ⅳ级组患儿IL-6、PCT和hs-CRP水平高于Ⅱ级组和Ⅲ级组，肺功能Ⅲ级组高于Ⅱ级组(n P<0.05)；肺功能Ⅳ级组患儿第一秒用力呼吸容积、最大呼吸峰流速、用力肺活量均低于Ⅱ级组和Ⅲ级组；肺功能Ⅲ级组低于Ⅱ级组，差异有统计学意义(n P<0.05)；血清IL-6、PCT及hs-CRP水平与肺功能等级呈正相关(n P<0.05)。n 结论:细菌感染性肺炎患儿血清IL-6、PCT及hs-CRP水平显著升高，且与肺功能等级呈正相关。“,”Objective:To explore the correlation between serum interleukin-6 (IL-6), procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP) levels and lung function in children with bacterial infectious pneumonia.Methods:A total of 210 children in Mengzhou People’s Hospital from May 2018 to September 2019 were recruited. According to the presence or absence of bacterial infectious pneumonia in this period, they were divided into positive group (n n=110) and negative group (n n=100). The serum IL-6, PCT and hs-CRP levels of the two groups were detected. Correlation analysis was performed in serum IL-6, PCT, hs-CRP levels and lung function.n Results:Compared with the negative group, The serum IL-6, PCT and hs-CRP levels in the positive group were significantly higher than those in the control group (n P<0.05). The serum IL-6, PCT and the hs-CRP levels of children in the pulmonary function grade IV group were significantly higher than those in the grade Ⅱ group and Ⅲ group, and the pulmonary function in grade Ⅲ group was significantly higher than that in the grade Ⅱ group (n P<0.05). The forced expiratory volume in the first second, minimum respiratory peak velocity, and forced vital capacity of lung function in grade Ⅳ group were significantly lower than those in grade Ⅱ group and grade Ⅲ group; lung function in grade Ⅲ group was significantly lower than that in grade Ⅱ group (n P<0.05); The serum IL-6, PCT and hs-CRP levels were positively correlated with lung function grade (n P<0.05).n Conclusions:The serum IL-6, PCT and hs-CRP levels increase significantly and are positively correlated with the grade of lung function in children with bacterial infectious pneumonia.