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观察了长期悬吊大鼠的睾丸、骨骼等器官的组织病理学变化。发现悬吊组动物睾丸实质萎缩,体积缩小,重量减轻,生精上皮细胞显著减少,甚至完全消失;睾丸间质中出现大量水肿液,间质细胞显著增生,部分动物睾丸间质出现大量多核巨细胞;睾丸间质血管内皮细胞增生,血管壁增厚和管腔狭窄。组织学测量表明,实验组股骨骺板软骨全层厚度、增殖带和肥大钙化带厚度以及股骨股干骨皮质厚度均少于对照组,其他器官仅见轻微病理变化。
The histopathological changes of the testis, bone and other organs in long-term suspended rats were observed. It was found that the testes in the suspension group showed substantial atrophy, reduced volume, reduced weight, significantly reduced or even completely disappeared in the seminiferous epithelium, large amounts of edema fluid in the testicular interstitium and significant proliferation of interstitial cells, Cells; testicular stromal vascular endothelial cell proliferation, vascular wall thickening and stenosis. Histological measurements showed that the total thickness of the cartilage, the thickness of the proliferative zone and the hypertrophic calcification zone, and the thickness of the cortical bone of the femoral shaft in the experimental group were less than those in the control group. Other organs showed slight pathological changes.