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支气管肺发育不良(bronchopulmonary dysplasia，BPD)是早产儿常见的慢性呼吸系统疾病，重度BPD病死率高，存活者常导致神经系统发育落后、心血管系统并发症及长期呼吸道问题而影响生存质量。目前尚无有效的治疗措施，多采取综合性治疗，包括营养支持、液体限制、呼吸支持、糖皮质激素及肺表面活性物质等，其有效性和安全性仍存在争议。本文综述重度BPD的管理现状。“,”Bronchopulmonary dysplasia(BPD) is a common chronic respiratory disease in preterm infants.Severe BPD(sBPD) features a high mortality rate, while for survivors, sBPD usually results in developmental retardation of the nervous system, cardiovascular complications, and long-term respiratory problems that affect the quality of life.At present, there are no effective treatment measures, and comprehensive treatments are adeptly more commonly, including nutritional support, fluid restriction, respiratory support, glucocorticoids, pulmonary surfactants and so on.Yet the effectiveness and safety of these treatments are still controversial.The article reviewed the current status of sBPD management.