目的:观察自拟和顺汤治疗反流性食管炎的临床疗效。方法:采用自拟和顺汤治疗RE患者42例,对照组采用奥美拉唑、吗丁啉、硫糖铝治疗38例。结果:巩固治疗后较治疗前相比差异有非常显著性意义(P<0.01);观察治疗后有效率80.95%,巩固治疗后有效率92.86%,巩固治疗后治疗组与对照组相比有显著性差异(P<0.01),两组药物副反应、胃镜检查结果比较差异均具有显著性意义(P<0.05)。结论:自拟和顺汤治疗反流性食管炎效果良好,巩固治疗后远期疗效更明显,且无明显毒副反应、疗效维持时间长。 Objective: To observe the clinical efficacy of self-made Heshun Decoction in the treatment of reflux esophagitis. Methods: Forty-two patients with RE were treated with self-made Heshun Decoction and the control group with omeprazole, domperidone and sucralfate for 38 cases. Results: After consolidation treatment, the difference was significant compared with that before treatment (P <0.01). The effective rate was 80.95% and the effective rate was 92.86% after consolidation treatment, and there was significant difference between the treatment group and the control group (P <0.01). There was significant difference between the two groups in side effects and gastroscopy (P <0.05). Conclusion: The treatment of reflux esophagitis by Heshun Decoction has a good effect, and the long-term curative effect is more obvious after consolidation treatment with no obvious side effects. The curative effect is maintained for a long time.