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爱尔兰都柏林骨髓移植中心因发生耐万古霉素肠球菌感染而关闭之后,欧洲骨髓移植协作组织发布了各国骨髓移植中心的感染情况的报告,报告调查了各国骨髓移植中心的感染,对病人发病率、死亡率的影响及1991年-2001年10年间移植手术情况。报告指出,共有13个骨髓移植中心发生了23次感染爆发,累及231例病人,从病人体内分离了10种细菌、8种病毒、5种真菌,有56例病人死于感染,所有死于细菌感染和大部分死于病毒感染的病人都来自接受移植手术的病人,在所有发生的感染爆发的事件中,主要是医源性感染包括病毒细菌及交叉感染。从骨髓移植病房的高效粒子过滤装置中分离包括全部8种病毒、4种细菌、3种真菌。欧洲骨髓移植协作组织共有12个骨髓移植中心部分或全部关闭。 (Bone Marrow Transplantation,2004,33:519-529.童卫杭,裴斐.)
After being closed due to vancomycin-resistant enterococcal infection in Dublin, Ireland, the European Bone Marrow Transplantation Coordination Organization released a report on the status of the infection at the bone marrow transplant centers in various countries. The report investigated the incidence of bone marrow transplant centers in various countries, The Impact of Mortality and Transplant Surgery during the 10 Years from 1991 to 2001. According to the report, 23 outbreaks occurred in 13 bone marrow transplant centers involving 231 patients. Ten bacteria, eight viruses and five fungi were isolated from the patient and 56 patients died of the infection. All died of bacteria Infection and the majority of patients who die from the virus are from patients who have undergone transplant surgery. In all cases of an outbreak of an infection, mainly iatrogenic infections include viral bacteria and cross-infection. All eight viruses, four bacteria and three fungi were isolated from the high efficiency particle filtration unit of the bone marrow transplantation ward. A total of 12 bone marrow transplant centers in the European Bone Marrow Transplantation Organization have been partially or totally closed. (Bone Marrow Transplantation, 2004, 33: 519-529. Tong Wei Hang, Fei Fei.)